New Agilent Altura SEC and PLRP-S HPLC Columns

Developing analytical methods that produce robust and reliable quantitative data is particularly challenging in liquid chromatography for analytes with acidic or anionic functional groups. This is due to their propensity toward nonspecific binding, or interactions with the active metal sites in the flow path. These interactions lead to sample loss due to adsorption, sample carryover, inconsistent peak area from injection to injection, increased peak tailing, and decreased signal response—especially with LC/MS workflows.

Altura columns feature Agilent's innovative Ultra Inert technology. This advanced coating blocks active metal sites, ensuring an inert flow path while maintaining the strength, pressure tolerance, and consistency of a traditional stainless steel HPLC column.

The result? Altura columns unlock the true separation potential of the stationary phase. Experience superior chromatographic performance, faster equilibration, and enhanced sensitivity for your most challenging metal-sensitive analytes.

The newest Altura Ultra Inert HPLC columns include wide-pore reversed-phase PLRP-S columns for protein LC/MS analysis and size exclusion (SEC) columns for analytes ranging from peptides to monoclonal antibodies to viral vectors and large oligonucleotides.

Key Features:
>  Reduced nonspecific binding for pure selectivity
>  Better peak shape with less tailing
>  Enhanced sensitivity due to improved sample recovery
>  Long lifetime due to robust coating and column packing
>  Rapid equilibration to get high-quality data faster
>  Versatile use with various chromatographic techniques
>  Readiness for evolving regulatory needs with lower limits of detection

Download the brochure for more information on the full line of Altura HPLC Columns with Ultra Inert Technology.